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Cloning and expression of brain catechol-o-methyltransferase

✍ Scribed by Lundström, K.; Tenhunen, J.; Tilgmann, C.; Ulmanen, I.

Book ID
123110154
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
106 KB
Volume
21
Category
Article
ISSN
0197-0186

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## Abstract Catechol‐o‐methyltransferase (COMT) is important for modulating dopamine levels, prefrontal cortex (PFC) function, and several psychiatric phenotypes. A single COMT mRNA has been described in human brain, which gives rise to membrane‐bound (MB)‐ and soluble (S)‐COMT proteins. In additio