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Cloning and Characterization of T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2), a Novel Guanine Nucleotide Exchange Factor Related to TIAM1

✍ Scribed by Choi-Ying Chiu; Song Leng; Kathleen A. Martin; Esther Kim; Susan Gorman; David M.J. Duhl


Book ID
115614862
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
687 KB
Volume
61
Category
Article
ISSN
0888-7543

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## Abstract Her‐2/__neu__ (__erb__B‐2) oncogene overexpression is associated with increased tumor progression and metastasis. Fatty acid synthase (FAS), the key lipogenic enzyme responsible for the endogenous synthesis of fatty acids, has been shown to be one of the genes regulated by Her‐2/__neu__

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