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Cloning and characterization of human complement component C7 promoter

✍ Scribed by González, S; Martínez-Borra, J; López-Larrea, C

Book ID: 110037432
Publisher: Nature Publishing Group
Year: 2003
Tongue: English
Weight: 205 KB
Volume: 4
Category: Article
ISSN: 1466-4879
DOI: 10.1038/sj.gene.6363902

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A C7 cDNA probe detecting a TaqI restriction fragment length polymorphism has been used to examine the segregation of the "silent allele" (C7\*Q0) in two familial deficiencies. Carrier diagnosis in healthy children is possible when both parents are heterozygotes. Only one of these two families was i