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Cloning and Characterization of cDNAs and the Gene Encoding the Mouse Platelet-Activating Factor Acetylhydrolase Ib α Subunit/Lissencephaly-1 Protein

✍ Scribed by Miklós Péterfy; Tibor Gyuris; David Grosshans; Christina C. Cuaresma; László Takács


Book ID
115614161
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
215 KB
Volume
47
Category
Article
ISSN
0888-7543

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The mammalian intracellular brain platelet-activating factor acetylhydrolase, implicated in the development of cerebral cortex, is a member of the phospholipase A2 superfamily. It is made up of a homodimer of the 45 kDa LIS1 protein (a product of the causative gene for type I lissencephaly) and a pa