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Cloning and Characterization of a Novel Zinc Finger Gene in Xp11.2

✍ Scribed by Jonathan M.J. Derry; Urda Jess; Uta Francke

Book ID
115612560
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
152 KB
Volume
30
Category
Article
ISSN
0888-7543

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We have identified a novel Kruppel-type zinc finger (ZF) gene, SKAT-2, which is selectively expressed by murine Th2 cells. The protein encoded by this gene has 14 C2H2-type ZF tandemly arrayed at its C terminus and N-terminal SCAN box and KRAB domains. SKAT-2 is tissue restricted in expression at th