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Cloning and Characterization of a Novel Class II Phosphoinositide 3-Kinase Containing C2 Domain

✍ Scribed by Hiroyuki Misawa; Motoaki Ohtsubo; Neal G. Copeland; Debra J. Gilbert; Nancy A. Jenkins; Akihiko Yoshimura

Book ID
115581780
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
860 KB
Volume
244
Category
Article
ISSN
0006-291X

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## Abstract The biological and pathophysiological significance of class II phosphoinositide 3‐kinase enzyme expression currently remains unclear. Using an in vitro scrape wound assay and time‐lapse video microscopy, we demonstrate that cell motility is increased in cultures expressing recombinant P