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Cloning and characterisation of the gene encoding HMG-CoA reductase from Taxus media and its functional identification in yeast

✍ Scribed by Liao, Zhihua; Tan, Qiumin; Chai, Yourong; Zuo, Kaijing; Chen, Min; Gong, Yifu; Peng�Wang, ; Pi, Yan; Tan, Feng; Sun, Xiaofen; Tang, Kexuan


Book ID
125490838
Publisher
Commonwealth Scientific and Industrial Research Organisation Publishing
Year
2004
Tongue
English
Weight
276 KB
Volume
31
Category
Article
ISSN
1445-4408

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## Summary A mutant of __Saccharomyces cerevisiae__ deleted for the __COQ3__ gene was constructed. __COQ3__ encodes a 3,4‐dihydroxy‐5‐hexaprenylbenzoate (DHHB) methyltransferase that catalyses the fourth step in the biosynthesis of ubiquinone from __p__‐hydroxybenzoic acid. A full length cDNA encod