The adrenergic agonist norepinephrine can exert its influence on cell function by activating both a-and 0-adrenergic receptors. In astrocytes, the a-adrenergic receptor activity of norepinephrine is known to inhibit the cyclic AMP response elicited by its action at p-adrenergic receptors. Pharmacolo
Clonidine inhibits the isoproterenol-induced desensitization of the beta noradrenergic activated adenylate cyclase system in astrocytes
β Scribed by W. J. Northam; P. L. Mobley
- Book ID
- 104655784
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 526 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0033-3158
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2-ketobutyrate and its analogues were found to inhibit strongly and transiently the rate of beta-galactosidase synthesis in Escherichia coli K12. This effect was ascribed to a strong and transient inhibition of the adenylate cyclase activity. By using pts mutants, we showed, in agreement with our pr