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Cloned truncated recA genes in E. coli

✍ Scribed by Sedgwick, Steven G. ;Yarranton, Geoffrey T.

Publisher: Springer
Year: 1982
Tongue: English
Weight: 548 KB
Volume: 185
Category: Article
ISSN: 0026-8925
DOI: 10.1007/bf00333796

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The ability of plasmids carrying truncated recA genes to sensitize recA+ cells to UV-irradiation was dependent upon the size of the cloned recA gene fragment. Radiosensitization correlated with the inhibition of recombinational repair, and the in vivo reduction of recA protein recombinase activity,

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