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Clonal heterogeneity of mantle cell lymphoma revealed by array comparative genomic hybridization

✍ Scribed by Liu, Fang; Yoshida, Noriaki; Suguro, Miyuki; Kato, Harumi; Karube, Kennosuke; Arita, Kotaro; Yamamoto, Kiyoko; Tsuzuki, Shinobu; Oshima, Koichi; Seto, Masao


Book ID
119828200
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
229 KB
Volume
90
Category
Article
ISSN
0902-4441

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## Abstract Nuclear variation in size and shape and genomic instability are hallmarks of dedifferentiated cancer cells. Although micronuclei are a typical long‐term consequence of DNA damage, their contribution to chromosomal instability and clonal diversity in cancer disease is unclear. We isolate