The clonal evolution of metastases from
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Lalarukh Khalique; Ayse Ayhan; John C. Whittaker; Naveena Singh; Ian J. Jacobs;
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Article
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2009
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John Wiley and Sons
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French
β 679 KB
## Abstract Several models of evolution from primary cancers to metastases have been proposed; but the most widely accepted is the clonal evolution model proposed for colorectal cancer in which tumors develop by a process of linear clonal evolution driven by the accumulation of somatic genetic alte