Clonal diversity of Shiga toxin-producing Escherichia coli O103:H2/H− in Germany

✍ Scribed by Rita Prager; Almut Liesegang; W. Voigt; W. Rabsch; Angelika Fruth; H. Tschäpe

• Book ID: 104443436
• Publisher: Elsevier Science
• Year: 2002
• Tongue: English
• Weight: 349 KB
• Volume: 1
• Category: Article
• ISSN: 1567-1348
• DOI: 10.1016/s1567-1348(02)00032-1

✦ Synopsis

Shiga toxin producing Escherichia coli O103:H2/H(-) belong to the third most frequently isolated EHEC serotypes in Germany following isolates of O157:H7/H(-) and O26:H11/H(-). A total of 145 respective E. coli 103 isolates from single cases of diarrhoea and haemolytic uremic syndrome (HUS) in 1997-2000 were characterised by a range of molecular subtyping methods (PFGE, P-gene profiling, ribotyping, electrotyping) and phage typing in order to analyse their genetic relatedness and the practicability for new epidemiological tracing back. All isolates cluster into a distinct EHEC subgroup and reveal a high clonal diversity together with a considerable stability. Since strains of this serotype rank up to the third most frequently isolated EHEC in Germany a large population of this serotype, and therefore, a great supply of such strains may exist in this country.