Clonal B-cell expansions in peripheral blood of HCV-infected patients
β Scribed by F. FRANZIN; D. G. EFREMOV; G. POZZATO; P. TULISSI; F. BATISTA; O. R. BURRONE
- Book ID
- 114714384
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 499 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0007-1048
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Evidence has been accumulating in favour of a role for hepatitis C virus (HCV) in the pathogenesis of human lymphoproliferative disorders. HCV infection has been documented in the majority of patients with essential mixed cryoglobulinaemia type II (MC-II); in patients with HCV infection, B-cell clon
## Abstract The presence of clonally restricted B lymphocytes in the peripheral blood of patients with multiple sclerosis (MS) was investigated using a cytofluorometric technique able to detect lymphocytes having homogeneous amounts of surface immunoglobulin of one light chain class. Thirtyβfive of