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CLOMIPRAMINE INFUSION AND LITHIUM CARBONATE: A SYNERGISTIC EFFECT ?

✍ Scribed by OFLANAGAN, P

Book ID
123319466
Publisher
The Lancet
Year
1973
Tongue
English
Weight
126 KB
Volume
302
Category
Article
ISSN
0140-6736

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A patient with a treatment-resistant depression of 15 months duration is reported. Initially he showed no response to clomipramine 150mg daily for 1 month. When lithium carbonate 600mg daily was added for 4 days he developed signs of lithium intoxication: drowsiness, confusion, and dystonia. After l