## Abstract As sensitization of leukemic cells with granulocyte colonyβstimulating factor (Gβcsf) can enhance the cytotoxicity of chemotherapy in acute myeloid leukemia (AML), a pilot study was conducted in order to evaluate the effect of Gβcsf priming combined with lowβdose chemotherapy in patient
Clofarabine with high dose cytarabine and granulocyte colony-stimulating factor (G-CSF) priming for relapsed and refractory acute myeloid leukaemia
β Scribed by Pamela S. Becker; Hagop M. Kantarjian; Frederick R. Appelbaum; Stephen H. Petersdorf; Barry Storer; Sherry Pierce; Jianqin Shan; Paul C. Hendrie; John M. Pagel; Andrei R. Shustov; Derek L. Stirewalt; Stephan Faderl; Elizabeth Harrington; Elihu H. Estey
- Book ID
- 108677406
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 150 KB
- Volume
- 155
- Category
- Article
- ISSN
- 0007-1048
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We sought to determine the role of granulocyte colony-stimulating factor (G-CSF) as an adjunct therapy in high-dose cytarabine-containing chemotherapy (HD C/T) for children with acute leukemia. Seventeen patients, aged 9 months to 18 years old, 8 ALL and 9 AML, were treated with cytarabine (Ara-C) 1
## Abstract ## Backgrounds and objectives The optimal strategy for the management of elderly patients with acute myeloid leukaemia (AML) is still controversial. We previously reported the effectiveness of low dose cytarabine (AraβC) and etoposide (VPβ16) (AV therapy) for those elderly AML patients