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Clocks and switches: bacterial gene regulation by DNA adenine methylation

✍ Scribed by David A Low; Josep Casadesús

Book ID
116747504
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
514 KB
Volume
11
Category
Article
ISSN
1369-5274

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Epigenetic regulation of metallothionein
Epigenetic regulation of metallothionein-i gene expression: Differential regulation of methylated and unmethylated promoters by DNA methyltransferases and methyl CpG binding proteins
✍ Sarmila Majumder; Huban Kutay; Jharna Datta; Dennis Summers; Samson T. Jacob; Ka 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 623 KB

## Abstract Metallothioneins (MTs) are a group of cysteine‐rich stress response proteins that scavenge reactive oxygen species and heavy metals. Recently, we have shown that MT‐I promoter is methylated and suppressed in some solid and liquid tumors and can be robustly activated following treatment