CLOCK: Calling time on bipolar disorder
β Scribed by Mark Greener
- Book ID
- 112175385
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2007
- Tongue
- English
- Weight
- 64 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1367-7543
- DOI
- 10.1002/pnp.19
No coin nor oath required. For personal study only.
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## Abstract Several previous studies suggest that dysfunction of circadian rhythms may increase susceptibility to bipolar disorder (BP). We conducted an association study of five circadian genes (__CRY2__, __PER1β3__, and __TIMELESS__) in a family collection of 36 trios and 79 quads (Sample I), and
## Abstract There are substantial abnormalities in the number, density, and size of cortical neurons and glial cells in bipolar disorder and schizophrenia. Because moleculeβmicroenvironment interactions modulate metabolite signals characteristics, these cellular abnormalities may impact transverse