✦ LIBER ✦

Clock and induction model for somitogenesis

✍ Scribed by Santiago Schnell; Philip K. Maini

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 79 KB
Volume: 217
Category: Article
ISSN: 1058-8388
DOI: 10.1002/(sici)1097-0177(200004)217:4<415::aid-dvdy8>3.0.co;2-3

No coin nor oath required. For personal study only.

✦ Synopsis

After many years of research, somitogenesis is still one of the major unresolved problems in developmental biology. Recent experimental findings show a novel type of pattern formation in which a signal sweeps along the presomitic mesoderm and narrows simultaneously as a new somite is formed. The signal then residues in the posterior half of the new somite, and another wave begins to sweep up from the caudal end. This behaviour is not easily explained by the existing theoretical models. We present a new model for somitogenesis that can account for this behaviour and is consistent with previous experimental observations.

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