## Abstract Alterations in expression of retinoid receptors are implicated in human cancers. We hypothesized that altered expression of retinoic acid receptors (RARΞ±,Ξ²,Ξ³) and retinoid X receptor RXRΞ± and their relationship with cell cycle regulators (p53, p16, p21) is associated with development, p
Clinicopathological significance and relations of Caspase-3 expression, cell proliferation and apoptosis in gastric cancer and the precancerous lesions
β Scribed by XiaoBin Hu; Jing Zhao; Lin Yang; Yan Xin
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 283 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1610-1979
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We analyzed a set of 103 non-small cell lung carcinomas (NSCLCs) for caspase-3, -6 and -8 expression and apoptosis. Additionally, the expression of bcl-2, bax and p53 were studied. Caspase-3 positivity appeared as diffuse, cytoplasmic staining and was restricted to the tumor area. In contrast, the i