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Clinicopathologic features and behavior of cutaneous eyelid melanoma

✍ Scribed by Mojgan Vaziri; Frank V Buffam; Magdalena Martinka; Allan Oryschak; Harjinder Dhaliwal; Valerie A White


Book ID
117327728
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
362 KB
Volume
109
Category
Article
ISSN
0161-6420

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## Abstract Germline mutations of the __PTEN__ tumor‐suppressor gene, on 10q23, cause Cowden syndrome, an inherited hamartoma syndrome with a high risk of breast, thyroid and endometrial carcinomas and, some suggest, melanoma. To date, most studies which strongly implicate PTEN in the etiology of s