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Clinically Relevant Biology of Hereditary Breast Cancer

✍ Scribed by William D. Foulkes


Book ID
114474090
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
115 KB
Volume
34
Category
Article
ISSN
0093-7754

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## Abstract To establish the importance of __CHEK2__ mutations for familial breast cancer incidence in the German population, we have screened all 14 of the coding exons in 516 families negative for mutations in both the __BRCA1__ and __BRCA2__ genes. We found 12 distinct variants in 30 unrelated p