Seventy-seven consecutive HBeAg-positive chronic hepatitis patients were studied from 1971 to 1983 to establish the seroconversion rate in the e system. Patients with less than a year of follow-up were not included in the study. Fifty-six patients with chronic active hepatitis (CAH) received immunos
Clinical, virologic and histologic outcome following seroconversion from HBeAg to anti-HBe in chronic hepatitis type B
β Scribed by Giovanna Fattovich; Massimo Rugge; Lucio Brollo; Patrizia Pontisso; Franco Noventa; Maria Guido; Alfredo Alberti; Professor Giuseppe Realdi
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 474 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0270-9139
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Data regarding the outcome of children with chronic hepatitis B after seroconversion are scarce. We describe the long-term evolution of these patients. One hundred and three children with antibody against hepatitis B e antigen and normal alanine aminotransferase (ALT) levels were followed for 0.6 to
Hepatitis B virus (HBV) strains from anti-HBe positive patients often show specific mutations in the precore gene, the core promoter region, or both. The dynamics of seroconversion in relation to the appearance of these mutations has not been studied and compared between defined HBV genotypes. Sampl