Clinical value of signal transducers and activators of transcription 3 (STAT3) gene expression in human osteosarcoma
β Scribed by Yu-Cai Wang; Lian-He Zheng; Bao-An Ma; Yong Zhou; Ming-Hua Zhang; Dian-Zhong Zhang; Qing-Yu Fan
- Book ID
- 113416183
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- German
- Weight
- 872 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0065-1281
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## Abstract Signal transducer and activator of transcription 3 (Stat3) is one of a family of cytoplasmic proteins that participate in normal cellular responses to cytokines and growth factors as transcription factors. Stat3 modulates various physiological functions including cell survival, cellβcyc
## Abstract Stat3 expression in cancer may have important prognostic and therapeutic value, but there has been no reports correlating Stat3 expression with prognosis in patients with osteosarcoma. The goal of this study is to correlate patient prognosis with the expression of Stat3 in osteosarcoma