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Clinical utility of novel mechanistic biomarkers of drug-induced liver injury

✍ Scribed by Antoine, Daniel J


Book ID
122627872
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
73 KB
Volume
221
Category
Article
ISSN
0378-4274

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## Abstract Limitations of existing biomarkers to detect liver injury in experimental animals highlight the need for additional tools to predict human toxicity. The utility of cytochrome c (cyt c) as a biomarker in serum and urine was evaluated in two rodent liver injury models. Adult Sprague–Dawle