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Clinical Trials of a Low Molecular Weight Matrix Metalloproteinase Inhibitor in Cancer

โœ Scribed by PETER D. BROWN

Book ID
119870217
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
339 KB
Volume
732
Category
Article
ISSN
0890-6564

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Low molecular weight inhibitors of matrix metalloproteinases can enhance the expression of matrix metalloproteinase-2 (gelatinase A) without inhibiting its activation
โœ Erika H. M. Kerkvliet; Ineke D. C. Jansen; Ton A. M. Schoenmaker; Andy J. P. Doc ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 180 KB

## Background: In the current study, the authors investigated the effects of synthetic low molecular weight inhibitors of matrix metalloproteinases (mmps) on the expression and activation of mmp-2 in a three-dimensional tissue system. ## Methods: Rabbit periosteal explants were cultured with or w