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Clinical trial of the estradiol vaginal ring in the U.S.

✍ Scribed by Lila E. Nachtigall

Book ID
116135618
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
415 KB
Volume
22
Category
Article
ISSN
0378-5122

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An unexpected enhanced release, in vitro, of estradiol (E2) was observed on the preparation of vaginal rings containing E2 and progesterone (P) in a silicone elastomer. The present work deals with exploring the reason(s) behind this enhanced E2 release. The effect of the ring design (i.e., putting P