In hepatitis C virus (HCV) genotype 1 infection, the duration of interferon-based therapy is a critical determinant in achieving sustained virologic response (SVR). Slow or late responders to peginterferon and ribavirin may benefit from an extended treatment course. We sought to determine if therapy
β¦ LIBER β¦
Clinical trial: extended treatment duration of peginterferon-alpha2b plus ribavirin for 72 and 96 weeks in hepatitis C genotype 1-infected late responders
β Scribed by M. NAGAKI; M. SHIMIZU; J. I. SUGIHARA; E. TOMITA; C. SANO; T. NAIKI; K. KIMURA; K. AMANO; T. SAKAI; M. NINOMIYA; T. KOJIMA; N. KATSUMURA; M. FUJIMOTO; H. MORIWAKI
- Book ID
- 108605671
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 214 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0269-2813
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The benefit of extending treatment duration with peginterferon (PEG-IFN) and ribavirin (RBV) from 48 weeks to 72 weeks for patients with chronic hepatitis C genotype 1 infection has not been well established. In this prospective, international, open-label, randomized, multicenter study, 1,428 treatm