Clinical studies of antibodies binding polyriboadenylic acid in systemic lupus erythematosus
β Scribed by Rao J. Pillarisetty; Norman Talal
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 385 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0004-3591
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π SIMILAR VOLUMES
Antibody a c t i v i t y t o various histones was examined i n a s o l i d phase radioimmunoassay. More than one h a l f o f the sera from systemic lupus erythematosus (SLE) p a t i e n t s had IgM a c t i v i t y t o t o t a l histones, and a s l i g h t l y lower frequency was observed f o r IgG a
Annexin V has a calcium-dependent binding affinity for anionic phospholipids and activated platelets, and prevents prothrombinase activity. We investigated the clinical significance of IgG anti-annexin V antibodies in patients with SLE. The study population consisted of 140 patients with SLE. Sera w