Clinical spectrum of CADASIL: a study of 7 families
β Scribed by H Chabriat; K Vahedi; M.G Bousser; M.T Iba-Zizen; A Joutel; A Nibbio; T.G Nagy; E Tournier Lasserve; M.O Krebs; J Julien; X Ducrocq; M Levasseur; J.L Mas; B Dubois; P Homeyer; O Lyon-Caen
- Book ID
- 118558586
- Publisher
- The Lancet
- Year
- 1995
- Tongue
- English
- Weight
- 879 KB
- Volume
- 346
- Category
- Article
- ISSN
- 0140-6736
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## Abstract Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary vascular disease that usually begins with migraine, followed by repeated strokes and progressive dementia. We describe an unusual clinical presentation of this condition
## Abstract Seven families with Xβlinked mental retardation (MR) have been studied clinically and cytogenetically. All affected males in six of the families were found to have a fragile site on Xq in a number of their peripheral lymphocytes. The fragile site was not seen in any of the affected male