Seven paediatric patients with symptomatic human immunodeficiency virus (HIV) infection were prospectively studied for 6-24 months after the start of intravenous immune globulin (IVIG) therapy. There was substantial clinical benefit during IVIG treatment with marked reduction of febrile and infectio
Clinical sleep patterns in human immune virus infection
β Scribed by David Wheatley; Kitty Smith
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 500 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0885-6222
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β¦ Synopsis
Clinical sleep patterns were recorded in 45 HIV+ve patients, using a 5-item questionnaire concerned with: sleep onset, nocturnal wakings, early morning awakening, duration of sleep and well-being on final waking. These were quantified to give a totd 'insomnia score' and compared to matched normal controls. Sleep was significantly worse in the HIV patients in relation to: delayed onset and early morning awakening (p < 03), nocturnal wakings and wellbeing on waking (p < O.OOOl), although not significant for duration of sleep. The mean total score for the HIV patients was 3.8 and for the controls 2.1 (p < 04001). There was an almost significant correlation between insomnia score and duration HIV+ve (p = 0055). AIDS status did not affect the results but the insomnia score was greater in the absence of anti-viral chemotherapy (p = 0-052). In the controls insomnia severity almost correlated to stress (p = 0.052). The results showed that the HIV patients had significantly more sleep disturbance than the matched controh, with resultant implications for improving quality of life in this respect.
π SIMILAR VOLUMES
Circulating immune complexes were quantitated in asymptomatic intravenous drug abusers (IVDA), male homosexuals, and patients with lymphadenopathy or acquired immunodeficiency syndrome (AIDS) by two different methods. Circulating immune coinplexes were elevated in HIV-seronegative