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Clinical significance of two mutations in the factor IX gene in a family with haemophilia B

✍ Scribed by A. SEXTON; J. FURMEDGE; C. BARNES; G. CHEETHAM; J. WALLACE; R. SAVARIRAYAN


Book ID
108775385
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
67 KB
Volume
16
Category
Article
ISSN
1351-8216

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Heteroduplex analysis in hemophilia B: D
✍ Driscoll, M. Catherine; Chu, Agnes; Hilgartner, Margaret W. πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 256 KB πŸ‘ 2 views

Heteroduplex analysis of polymerase chain reaction (PCR)-amplified factor IX (FIX) sequences in eight hemophilia B pedigrees localized the causative hemophilia mutation to a single exon in each case. Subsequent PCR-based direct DNA sequence analysis ldentifled two novel FIX mutations and SIX recurre