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Clinical significance of RECK promoter methylation in pancreatic ductal adenocarcinoma

✍ Scribed by Xiong-Xiong Lu, Shu-Min Zhang, Yuan Fang, Zheng-Ting Wang, Jun-Jie Xie…

Book ID
120719594
Publisher
S. Karger AG
Year
2013
Tongue
English
Weight
178 KB
Volume
34
Category
Article
ISSN
1010-4283

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## Abstract Loss of menin, a tumor suppressor coded by the __MEN1__ gene, is a key factor in the pathogenesis of multiple endocrine neoplasia type I and in a percentage of sporadic endocrine tumors of the pancreas and parathyroid glands. This study investigated expression of the menin protein in th