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Clinical significance of hepatocyte growth factor, platelet-derived growth factor-AB, and transforming growth factor-α in bone marrow and peripheral blood of patients with multiple myeloma

✍ Scribed by Ismail Oguz Kara; Berksoy Sahin; Ramazan Gunesacar; Cagatay Unsal

Publisher
Springer Healthcare Communications
Year
2006
Tongue
English
Weight
232 KB
Volume
23
Category
Article
ISSN
0741-238X

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## Abstract Hepatocyte growth factor (HGF) has been shown to be involved in angiogenesis, epithelial cell proliferation, and osteoclast activation. HGF and its receptor are expressed on myeloma cell lines and could be involved in the pathogenesis of bone destruction in multiple myeloma (MM). The ai