The significance of antibodies to hepatitis C virus in patients with chronic alcoholic liver disease is unclear. Prior studies have utilized the first-generation enzyme-linked immunosorbent assay, which is limited by problems with sensitivity and specificity. Hepatitis C virus infection in 137 pati
Clinical Significance of Hepatitis GB Virus C Infection in Alcoholic Liver Disease
β Scribed by Mikihiro Tsutsumi; Makoto Sawada; Shujiro Takase; Wun-Bil Chen; Yasuhiro Ueshima; Mutsumi Tsuchishima; Koshi Shimanaka; Tohru Itoh; Hiromu Kawahara
- Book ID
- 109119923
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 820 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0145-6008
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A novel RNA virus of the Flaviviridae family has been discovered recently and designated hepatitis GB-C virus (GBV-C). Previous studies have reported that GBV-C is associated with posttransfusion hepatitis, chronic viral hepatitis, and cryptogenic hepatitis. However, the clinical significance of GBV
W e evaluated hepatitis B virus DNA and hepatitis C virus RNA in sera from 110 HBsAg and IgM HBc antibody-negative heavy drinkers (50 cirrhosis, 13 chronic active hepatitis, 25 fatty liver with or without mild to moderate fibrosis, alcoholic hepatitis or both and 22 healthy alcoholic subjects) with
## Abstract The clinical and virological significance of lowβlevel viremia by hepatitis B virus (HBV) in hepatitis C virus (HCV)βinfected patients remains unclear. HBVβDNA and HCVβRNA were, therefore, quantitatively analyzed in livers and sera from coβinfected patients. HBVβDNA and HCVβRNA were qua
Infection with putative non-A to E hepatitis virus, designated GB virus C (GBV-C), was surveyed in 286 patients with chronic liver disease in Japan. RNA of GBV-C was detected, by reverse-transcription polymerase chain reaction with nested primers from the 5'-noncoding region, in 19 patients (6.6%) a