Evaluation of skin damage caused by perc
β
Yasuko Obata; Takahiro Sesumi; Kozo Takayama; Koichi Isowa; Sharon Grosh; Steve
π
Article
π
2000
π
John Wiley and Sons
π
English
β 158 KB
π 1 views
Fractal analysis of the cross-sectional morphology of rat skin was conducted to evaluate pathologic changes evoked by percutaneous absorption enhancers. Male hairless rats (WBN/Ht-ILA), 8 weeks old, weighing 160 to 180 g were used. Under anesthetization, glass cells (10-mm inner diameter) were attac