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Clinical response of myelodysplastic syndromes patients to treatment with coenzyme Q10

โœ Scribed by Naomi Galili; Eric V. Sechman; Jan Cerny; Murtaza Mehdi; Muhammad Mumtaz; Peter Westervelt; Jessica Maguire; Azra Raza

Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
665 KB
Volume
31
Category
Article
ISSN
0145-2126

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We studied the immune compartment in patients with myelodysplastic syndromes. We show increased surface expression of activation markers (HLA-DR(+), CD57(+), CD28(-), CD62L(-)) on T lymphocytes in blood and bone marrow (n=131). T cell activation was not restricted to any relevant clinical subgroup (

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## Abstract ## BACKGROUND Approximately 15,000 new cases of myelodysplastic syndromes (MDS) are expected in the United States each year. ## METHODS The mainstay for the management of myelodysplastic syndromes (MDS) is supportive therapy with red blood cell (RBC) transfusions to improve the patie