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Clinical response and plasma concentration of amitriptyline and its metabolite nortriptyline

✍ Scribed by S. Vandel; B. Vandel; M. Sandoz; G. Allers; P. Bechtel; R. Volmat


Publisher
Springer
Year
1978
Tongue
English
Weight
461 KB
Volume
14
Category
Article
ISSN
0031-6970

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Methods for the estimation of the tricyclic antidepressants in plasma have been described employing UV spectrophotometry', gas-liquid chromatographyz4, and mass fragmentography5-6. UV methods, while adequate for analysis in cases of overdose, are insufficiently sensitive where plasma IeveIs are req