## Abstract ## BACKGROUND Recently, an internal tandem duplication of the __FLT3__ gene (__FLT3__/ITD) was found in approximately 20% of adult acute myeloid leukemia (AML) cases and associated with a poor outcome. However, there are few studies on __FLT3__/ITD in childhood AML, and the clinical si
Clinical relevance of in vitro chemoresistance in childhood acute myeloid leukemia
β Scribed by Yamada, S; Hongo, T; Okada, S; Watanabe, C; Fujii, Y; Ohzeki, T
- Book ID
- 110055059
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 132 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0887-6924
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Patients with newly diagnosed acute myeloid leukaemia (AML) are increasingly being enrolled in clinical trials sponsored by pharmaceutical companies or the National Cancer Institute. These trials routinely exclude patients who are less likely to respond (LLTR), e.g. those with Zubrod pe
## Abstract Nowadays about twoβthirds of children with acute lymphoblastic leukemia (ALL) can be cured with chemotherapy, but oneβthird die from the disease. The clinical response of leukemic cells to chemotherapy is roughly due to two factors: the effective drug levels reaching the cells and the r