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Clinical relevance of imaging proliferative activity in lung nodules

✍ Scribed by Andreas K. Buck; Martin Hetzel; Holger Schirrmeister; Gisela Halter; Peter Möller; Clemens Kratochwil; Andreas Wahl; Gerhard Glatting; Felix M. Mottaghy; Torsten Mattfeldt; Bernd Neumaier; Sven N. Reske


Publisher
Springer
Year
2004
Tongue
English
Weight
407 KB
Volume
32
Category
Article
ISSN
0340-6997

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The pathway consisting of retinoblastoma protein (pRB), cyclin D1 and p16 (RB pathway) which is involved in the phosphorylation of pRB plays an important role in G 1 /S progression. The disruption of this RB pathway has been reported in several types of human neoplasm. An immunohistochemical study o