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Clinical relations of methotrexate pharmacokinetics in the treatment for pediatric osteosarcoma

✍ Scribed by Marta Hegyi, Ágnes Gulácsi, Edit Cságoly, Katalin Csordás, Olivér T. Eipel, Dániel J. Erdélyi, Judit Müller, Karolina Nemes, Orsolya Lautner-Csorba, Gábor T. Kovács

Book ID
118785426
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
323 KB
Volume
138
Category
Article
ISSN
1432-1335

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A new program package (PharmCalc) has been developed for the calculation of basic pharmacokinetic parameters (half-time, systemic clearance, renal clearance, AUC, volume of distribution, CSF/serum distribution ratio) of methotrexate (MTX). The program helps in the early recognition of patients at ri