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Clinical psychopharmacology research in geriatrics: An agenda for research

✍ Scribed by Lon S. Schneider; Rick A. Martinez; Barry D. Lebowitz

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
509 KB
Volume
8
Category
Article
ISSN
0885-6230

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The two main areas of geriatric clinical psychopharmacology research, depression and dementia, are reviewed. The issues for depression research include pharmacokinetics in the geriatric population and the relationship to efficacy and side‐effects; the treatment of the medically ill and the very old; and maintenance and continuation treatments. In particular, the recommendations from the recently convened NIH Consensus Development Conference for the Diagnosis and Treatment of Depression in Late Life are discussed. The issues in dementia research include effective treatment of behavioral symptoms as well as severe and mild cognitive impairment; the development of better cholinesterase inhibitors; the application of other drugs; and the use of appropriate clinical trials methodology.

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