Merosin and congenital muscular dystroph
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Miyagoe-Suzuki, Yuko; Nakagawa, Masahiro; Takeda, Shin'Ichi
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Article
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2000
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John Wiley and Sons
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English
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Merosin (also called as Laminin-2) is an isoform of laminin comprised of the โฃ2, โค1 and โฅ1 chains. In European populations, half of the patients with classical congenital muscular dystrophy have mutations of the LAMA2 gene (6q22-23) and present reduced or absence of laminin โฃ2 chain. This form is ge