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Clinical phenotype of posterior polymorphous corneal dystrophy in a family with a novel ZEB1 mutation

✍ Scribed by Dan Q. Nguyen; Mohsen Hosseini; Gail Billingsley; Elise Héon; Amanda J. Churchill


Book ID
118075668
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
232 KB
Volume
88
Category
Article
ISSN
1755-375X

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✍ Petra Liskova; Stephen J. Tuft; Rhian Gwilliam; Neil D. Ebenezer; Katerina Jirso 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 99 KB

We describe the search for mutations in six unrelated Czech and four unrelated British families with posterior polymorphous corneal dystrophy (PPCD); a relatively rare eye disorder. Coding exons and intron/exon boundaries of all three genes (VSX1, COL8A2, and ZEB1/TCF8) previously reported to be imp