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Clinical, pharmacologic, and immunologic effects of 2'-deoxycoformycin

✍ Scribed by Spremulli, E N; Parks, R E; Calabresi, Paul; Cummings, F J; Crabtree, G W; Wiemann, M C


Book ID
109844404
Publisher
Nature Publishing Group
Year
1988
Tongue
English
Weight
902 KB
Volume
44
Category
Article
ISSN
0009-9236

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## Abstract The monoclonal antibody trastuzumab and the EGFR/HER2 tyrosine kinase inhibitor lapatinib improve the clinical outcome of patients with HER2‐overexpressing breast cancer. However, the majority of metastatic cancers will eventually progress, suggesting the need for other therapies. Becau