𝔖 Bobbio Scriptorium
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Clinical pharmacokinetics of isradipine

✍ Scribed by Horst F. Schran; James M. Jaffe; Leonard M. Gonasun

Book ID
115682197
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
850 KB
Volume
84
Category
Article
ISSN
1555-7162

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The pharmacokinetics of isradipine, a calcium-channel blocker, have been studied in eight patients on chronic haemodialysis. A single oral dose of 5 mg was administered on both a non-haemodialysis and a haemodialysis day and the plasma concentrations of isradipine were analyzed. The mean cmax, tmax,

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The pharmacokinetics of the dihydropyridine calcium antagonist isradipine has been examined in 8 healthy volunteers, 7 patients with non-cirrhotic chronic liver disease (CLD), and 8 patients with biopsy-proven cirrhosis (CIR). Isradipine was simultaneously given orally (12C 5 mg) and i.v. (13C 1 mg)