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Clinical Pharmacokinetics of Amlodipine

โœ Scribed by Meredith, Peter A.; Elliott, Henry L.

Book ID
120444085
Publisher
Springer International Publishing AG
Year
1992
Tongue
English
Weight
869 KB
Volume
22
Category
Article
ISSN
0312-5963

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It was reported that gastric motility was delayed and gastric acid secretion was reduced in vagotomized dogs which mimics a low gastric acidity in humans. A delay in gastric motility causes long residence of amlodipine in the stomach. More unionized fractions of amlodipine could exist in less acidic