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Clinical implications of SOCS1 methylation in myelodysplastic syndrome

✍ Scribed by Shang-Ju Wu; Ming Yao; Wen-Chien Chou; Jih-Luh Tang; Chien-Yuan Chen; Bo-Sheng Ko; Shen-Yi Huang; Woei Tsay; Yao-Chang Chen; Ming-Ching Shen; Chiu-Hwa Wang; Yo-Chia Yeh; Hwei-Fang Tien

Book ID
108673954
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
178 KB
Volume
135
Category
Article
ISSN
0007-1048

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Aberrant methylation in pediatric myelod
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✍ Daniel O. Vidal; ValΓ©ria A. PaixΓ£o; Mariana Brait; Elisabeth X. Souto; OtΓ‘via L. πŸ“‚ Article πŸ“… 2007 πŸ› Elsevier Science 🌐 English βš– 212 KB

## Background: Aberrant methylation of gene promoter region is responsible for inappropriate gene silencing, and it has been associated to initiation and progression of cancer. aberrant promoter methylation is frequently observed in adult patients with myelodysplastic syndrome (mds), but in pediatr