𝔖 Bobbio Scriptorium
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Clinical implications of insulin-like growth factor 1 system in early-stage cervical cancer

✍ Scribed by Huang, Y-F; Shen, M-R; Hsu, K-F; Cheng, Y-M; Chou, C-Y


Book ID
109999755
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
218 KB
Volume
99
Category
Article
ISSN
0007-0920

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## Insulin -like growth factor I (IGF-I) is a potent mitogen for human breast-cancer cells in vitro. In circulation, most of IGF-I is bound to IGF-binding protein 3 (IGFBP-3). This high-affinity binding is thought to have an important limiting effect on the availability of IGF-I for biological act