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Clinical implications of drug interactions with the cytochrome P-450 enzyme system associated with omeprazole

✍ Scribed by Thomas J. Humphries

Book ID
112509224
Publisher
Springer US
Year
1991
Tongue
English
Weight
478 KB
Volume
36
Category
Article
ISSN
0163-2116

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The magnitude of drugΒ±drug interactions in vitro involving competitive inhibition of cytochrome (CYP) isozymes by newer antidepressants can theoretically be shown to be dependent upon several factors. These include the concentration of both the substrate and inhibitor, the anity of the inhibitor for