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Clinical implications of der(9q) deletions detected through dual-fusion fluorescence in situ hybridization in patients with chronic myeloid leukemia

✍ Scribed by Mireille Guimarães Vaz de Campos; Fábio Tadeu Montesano; Maria Madalena Rodrigues; Maria de Lourdes Lopes Ferrari Chauffaille

Book ID: 113513196
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 423 KB
Volume: 178
Category: Article
ISSN: 0165-4608
DOI: 10.1016/j.cancergencyto.2007.06.013

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## Abstract Chronic myeloid leukemia (CML) is characterized by the presence of a t(9;22)(q34;q11.2), which leads to the well‐known BCR–ABL1 fusion protein. We describe a patient who was diagnosed clinically with a typical CML but on cytogenetic analysis was found to have a t(9;22)(p24;q11.2). Chrom